About the Antivirus False Positive

Turn off ANTIVIRUS Protection while using the PCUAE setups, if not then it will stop you running the Setup files.
Turn off Real Time Protection, it will turn itself back on later by itself, the virus its seeing is a false positive in the setup.exe files so is not real, it will not allow you to run the setup.exe files until you turn it off or it will remove the setup.exe file from the folder its downloaded it too and move it to the Antivirus Quarantine Vault, you can move it back to the folder in the Antivirus Projection History Option in its settings, you can Exclude the folder its downloading the Setup files too and you will not need to Turn off Real Time Protection anymore.

There is nothing that can be done about it, it because PCUAE runs scripts inside it that it needs and the antivirus software can see them in the setup.exe files so thinks it infected or is a virus, its because Antivirus Software can not see the difference between them, if they are a real virus or not one, antivirus software need making so it can tell the difference so made better then it is, it always has this problem.